Two weeks prior to your trip,
1) Check all of your appliances, propane tanks, battery, water pump, toilet.
2) Flush your clean water tank out with bleach tablets.
3) Check tire pressure. We have a portable air compressor so that you don't have to bring your trailer into a gas station. The compressor also has an adaptor for inflating rafts and other toys.
If this is your first trip, do a dry run of your set up routine, complete with leveling and unroll your awning. I recommend 2 weeks in advance in case you have to repair anything or order parts.
From start to finish, it took about an hour. 25 minutes were dedicated to the awning (this took two 6' 2" men) - obviously, we didn't know what we were doing (that's why we did a dry run!) The rest of the time was spent figuring out how to pull the trailer 20 feet on a relatively level driveway towards the street with a trailer dolly and then leveling it. Again, so glad we did this because imagine pulling up just before sunset and trying to figure all this out in near darkness on an unpaved plot.
My son and I decided to go all out and sleep in La Palace. I used regular house bedding and it started out a bit chilly but bearable and continued to get colder towards dawn. I think with my sleeping bag zipped to keep more body heat in, I will be fine in a real world situation.
While I was emailing and surfing the net on my iPad just before bed (roughing it, I know) I received an email from my friend who informed me that part of Hwy 1 leading to Big Sur (my intended maiden voyage in 2 weeks) was closed due to a landslide. Which leads me to the last tip: Check road conditions! You just never know whether nature (or construction) will derail your trip. We have adjusted our plans accordingly and will now be going to Capitola.
ECT (Extra Comfort Tip):
For those who don't like to wake up at the crack of dawn (moi), pack an eye mask to block out the sunlight which I have discovered is abundant out in nature (duh!)